Abstract: The study examined the effects of care and support provided by family members of people living with HIV/AIDS (PLWHA) on their agricultural livelihoods in Benue state, Nigeria. Data were collected from a purposively selected sample of 96 family members of PLWHA through interview guide and focus group discussions. The data collected were subjected to descriptive and inferential (regression analysis) statistics. Effects of care on agricultural livelihoods was based on differences in farm size, time spent on farm and farm labour of family members before and after infection of PLWHA. Few (3.1%) of the family members had their farm size reduced by 0.30 ha and 1.0% lost 10 ha after a member was infected; 11.5% of the respondents lost 1 h; 1.0% lost 2 h and 62.5% lost 8 h due to care offered. It was found that 27.1% of the respondents had their farm labour increased by 1 man day^-1, 18.8% by 2 man day^-1 and 1.0% by 7 man day^-1 while 52.1% lost the total labour on their farms. The result of the ordinal regression analysis showed that care offered significantly determined farm size (β = -0.899, R² = 0.044, p = 0.046) indicating that increase in care will reduce farm size of family members by 89.9%. The study therefore recommends that intervention programme that is aimed at improving the knowledge of the family and community members about care and support for PLWHA should be designed. Extension workers’ activities in Benue state should be geared towards improving the knowledge of family members of PLWHA on the practice of alternative types of farming that is less labour and time consuming. Relevant stakeholders should intensify their efforts towards care and support.