Authors : M. Opige , E. Kateyo , J.D. Kabasa and D. Olila
Abstract: Antibacterial resistance is a world wide growing problem. Isolation of microbial agents less susceptible to regular antibiotics and recovery of resistant isolates during antibacterial therapy is increasing throughout the world. One of the measures to combat the increasing rate of resistance is to have a continuous investigation for new, safe and effective antimicrobials as alternative agents to substitute with no-effective ones. In this study the efficacy of selected mushrooms of Teso region (Kumi District) against common bacteria was investigated. Antibacterial assays were done using methanol and petroleum ether extracts from mushrooms and Agar Well Diffusion Method and study Disc Methods were used to demonstrate activity. It was noted that E. coli was resistant to most petroleum ether and methanol extracts. Also S. aureus was significantly inhibited by petroleum ether extracts while P. aeruginosa, a very resistant bacterium always, was significantly inhibited by the methanol extracts. These activities might be of some practical importance if the chemical compounds inducing activity are known. Further studies should therefore be done to confirm and extend the present findings, working on a broader range of species.
M. Opige , E. Kateyo , J.D. Kabasa and D. Olila , 2006. Antibacterial Activity of Extracts of Selected Indigenous Edible and Medicinal Mushrooms of Eastern Uganda. International Journal of Tropical Medicine, 1: 111-116.