Abstract: The antibody (Ab) responses in chicks vaccinated against infectious bursal disease (IBD) and Newcastle disease (ND) using combined and single vaccination regimes were determined. Three vaccination routes namely aerosol, intranasal (I/N) and drinking water (DW) were used. Enzyme-linked immunosorbent assay (ELISA) was employed to measure the Ab responses to the vaccines. Generally, better Ab responses were observed for both vaccines when given in a single form as compared to the combined form except for the IBD when given in DW with non-significant (P<0.05) difference and for ND when given in aerosol with significant (P<0.05) difference. However, the overall combined vaccination gave better Ab responses than single vaccination. The highest Ab response noted for IBD was when the vaccine applied via the aerosol in a single form whereas the highest Ab response for ND was noted when the vaccine applied via the aerosol in a combined form. In conclusion, the results obtained revealed that better Ab responses for the vaccines were obtained when they administered via the aerosol. It is, therefore, recommended to vaccinate the chicks against IBD and ND via the aerosol with the vaccines in a combined form as the way described in this scientific communication.
M. H.Tabidi , A.Makkawi , E. Mahasin and A. S. Ali , 2004. The Serological Responses in Chicks Vaccinated with Combined or Single Infectious Bursal Disease and Newcastle Disease Vaccines . Journal of Animal and Veterinary Advances, 3: 9-12.