Authors : Siamak Saifzadeh , Rahman Oroujzadeh , Aliasghar Tehrani and Farnood Shokouhi Sabet Jalali
Abstract: November 13, 2006This study was performed to evaluate the enhancing effect of garlic (1% aqueous extract) on the wound healing in an animal model. Five apparently healthy mongrel dogs of both sexes, weighed 20-25 kg were studied. Two rectangular (2� cm2) wounds were created on the left (experiment) and right (control) caudodorsal areas of each dog. The experiment wounds were treated with 0.5 mL of 1% aqueous garlic extracts every 3 other day for 30 days. The wounds were photographed and compared for rate of wound contraction with digital scanning software. Specimens were taken for histopathological examinations on day 30. Significant differences were seen between the experiment and control wounds for the rate of contraction. On histopathology re-epithelization was more pronounced and the collagen fibers were also more orderly arranged in the experiment group. It is concluded that topical application of aqueous garlic extract, as used in this study could improve rate of wound healing in the dog.
Siamak Saifzadeh , Rahman Oroujzadeh , Aliasghar Tehrani and Farnood Shokouhi Sabet Jalali , 2006. Enhancing Effect of Aqueous Garlic Extract on Wound Healing in the Dog: Clinical and Histopathological Studies . Journal of Animal and Veterinary Advances, 5: 1101-1104.