Authors : K. Mejia-Martinez , C. Lemus-Flores , J.F. Zambrano-Zaragoza , R. Ramirez-Necoechea , D. Mota-Rojas and M. Alonso-Spilsbury
Abstract: The aim of the study was to measure the cytokine immune response in 2 Mexican creole biotypes and compare it to commercial pigs (COM) as disease resistance indicators. Twenty six commercial (COM), 25 Cuino (CP) and 25 Mexican hairless (MHP) pigs were vaccinated with a commercial bacterin containing Salmonella, E. coli and Pasteurella at 45 days of age; a sample was taken a week later to test serum levels of interleukin 1 (IL-1 ), interleukin 4 (IL-4), interferon-gamma (INF- ) and alfa tumor necrosis factor (TNF- ). Cytokine quantification serum tests were carried out with commercial kits using the ELISA sandwich method. The Kruskal-Wallis test was used to compare cytokine concentrations and the Wilcoxon test was run to look for differences among breeds. IL-1 and IL-4 production was higher in HMS as compared to the other breeds. No significant differences between INF- and TNF- production were seen. Results suggest that MHP have a higher response capacity before an infection, compared to the other breeds.
K. Mejia-Martinez , C. Lemus-Flores , J.F. Zambrano-Zaragoza , R. Ramirez-Necoechea , D. Mota-Rojas and M. Alonso-Spilsbury , 2008. Cytokine Immune Response in Mexican Creole and Commercial Pigs Under Uncontrolled Conditions. Journal of Animal and Veterinary Advances, 7: 625-629.