Authors : Hasan Icen, Servet Sekin, Simten Yesilmen, Nurettin Isik and Aynur Simsek
Abstract: We tested the field efficacy of a new antibiotic tulathromycin in the treatment of naturally occuring bovine respiratory disease beef calves with rectal temperatures >39.5°C and signs compatible bovine respiratory disease were entered into the trial. This study was performed on 30 mixed-breed beef calves with bronchopneumonia, 8-10 months old. Bacteriological and serological examinations were performed in nasal swabs and blood samples collected from beef calves. Klebsiella pneumoniae, Mannheimia haemolytica, Coagulase (+) Staphylococcus and Streptococcus sp. were isolated from bacteriological examinations of bronchoalveolar lavage. Serum samples were tested serologically for antibodies to Infectious bovine rhinotracheitis, Parainfluenza-3, Bovine adenovirus and Bovine viral diarrhea viruses. All samples were positive for antibodies to Infectious bovine rhinotracheitis, Parainfluenza-3, Bovine adenovirus and Bovine viral diarrhea viruses. Calves were assigned to receive tulathromycin (2.5 mg kg-1 bodyweight, subcutaneously). Clinical measures of efficacy included mortality, rectal temperatures, pulsation, respiratory rate, assesment of treatment succes or failure and number of relapses. Four calves relapses and needed second enjection. No significant adverse reactions were noticed with tulathromycin. After the treatment, all the calves were cured. Results indicate that tulathromycin administration was found to be effective in the treatment of bovine respiratoy diseases (especially in bacterial infections) of beef calves in region of Diyarbakir.
Hasan Icen, Servet Sekin, Simten Yesilmen, Nurettin Isik and Aynur Simsek, 2009. Viral and Bacterial Pathogen Isolated and Identified from Pneumonic Calves in Region of Diyarbakir and its Treatment with Tulathromycin. Journal of Animal and Veterinary Advances, 8: 1545-1550.