Abstract: This study was designed to evaluate the feasibility of laparoscopic partial hepatectomy by using the intracorporeal horizontal interrupted mattress suture technique. Ten Black Iraqi local old goats of both sexes were used. Animals divided into two equal groups. Laparoscopic partial hepatectomy were performed in both groups comparing horizontal interrupted mattress suture by using polygalactine synthesis absorbable suture material, to suture around the resected part as a triangular in shape. Then resected this a triangular area and without approximate of resected edge in group, A. While the same method in group B but with approximation of the resected edge by simple interrupted suture pattern. The animals were inspected laparoscopically, one month post operation, which revealed that the regeneration of the resected site was better in group, B compared with group, A. In addition to that the adhesion of the resected site with adjacent structures were slight in degree in group, B than in group, A. This technique of intracorporeal horizontal interrupted mattress suture provides to be feasible and can be used in laparoscopic partial liver resection of the peripheral abnormal lesion.