Abstract: The swine enteric disease, porcine epidemic diarrhea is caused by Porcine Epidemic Diarrhea Virus (PEDV). The disease continues to be economically significant in the swine industry especially in outbreak events. One of the prerequisites in disease management and epidemiological investigations is knowledge of factors underlying disease transmission and spread. The susceptibility of mice to PEDV was investigated as vectors in transmission. To prove this possibility, specific pathogen free mice were inoculated through oral, intranasal and intraperitoneal routes and investigate the presence of virus in tissues. As per results, PEDV was not able to replicate in the mice and there was no antibody reaction indicating that they are implausible vectors in PEDV transmission.
N.A. Kamau, J.Y. Park, J.E. Park, B.H. Hyun, D.K. Yang, J.Y. Song and H.J. Shin, 2010. Susceptibility of Mice to Porcine Epidemic Diarrhea Virus. Journal of Animal and Veterinary Advances, 9: 3114-3116.