Search in Medwell
 
 
Journal of Animal and Veterinary Advances
Year: 2012 | Volume: 11 | Issue: 9 | Page No.: 1350-1352
DOI: 10.3923/javaa.2012.1350.1352  
Distribution of Allele Frequency at PNLIP rs41648172 Between Japanese Black and Four Other Cattle Breeds with Differing Historical Selection for Marbling
Hideki Tanomura , Youji Muramatsu , Takuji Yamamoto , Takeshi Ohta , Hiroyuki Kose and Takahisa Yamada
 
Abstract: Marbling defined by the amount and distribution of intramuscular fat, so-called Shimofuri is an economically important trait of beef cattle in Japan. Researchers have recently reported that a Single Nucleotide Polymorphism (SNP) referred to as rs41648172 in intron 6 region of the Pancreatic Lipase (PNLIP) gene which have been considered as a positional functional candidate for the gene responsible for marbling was associated with marbling in Japanese Black beef cattle with the T allele being associated with a high level of marbling. In this study, researchers investigated the allele frequency distribution of the rs41648172 SNP among the 5 cattle breeds, Japanese Black, Japanese Brown, Japanese Short Horn, Holstein and Brown Swiss breeds. The T allele at the rs41648172 SNP associated with high marbling was found at higher frequency in Japanese Black breed that has been subjected to a strong selection for high marbling than in the other breeds that have not been strongly selected for high marbling. Based on this finding, researchers hypothesized that the pressure of the strong selection for high marbling in the Japanese Black breed has increased the frequency of the T allele at the rs41648172 SNP in the PNLIP. This study, together with the previous association study, suggested that the PNLIP SNP may be useful for effective marker-assisted selection to increase the levels of marbling.
 
How to cite this article:
Hideki Tanomura, Youji Muramatsu , Takuji Yamamoto , Takeshi Ohta , Hiroyuki Kose and Takahisa Yamada , 2012. Distribution of Allele Frequency at PNLIP rs41648172 Between Japanese Black and Four Other Cattle Breeds with Differing Historical Selection for Marbling. Journal of Animal and Veterinary Advances, 11: 1350-1352.
DOI: 10.3923/javaa.2012.1350.1352
URL: http://medwelljournals.com/abstract/?doi=javaa.2012.1350.1352