Authors : Zhuoying Zhang and Jinyang Lin
Abstract: The main purpose of this study was to investigate the effects of polysaccharides from the roots of Achyranthes bidentata (ABP) on exhaustive exercise-induced oxidative stress by measuring related biochemical parameters of rats. The animals were randomly divided into four groups (n = 10 in each group): one control group and three ABP administered groups. The control group was given saline solution and the administered groups were given different doses of ABP (50, 100, 200 mg kg-1) by gavage once a day. After 21 days, the rats performed an exhaustive exercise test on a graded treadmill, along with the determination of related oxidative stress parameters. The results showed that ABP could significantly increase Superoxide Dismutase (SOD), Glutathione Peroxidase (GSH-Px) and Catalase (CAT) activities, decrease Malondialdehyde (MDA) contents in muscle of rats which meant that ABP effectively attenuates oxidative stress induced by exhaustive exercise.
Zhuoying Zhang and Jinyang Lin, 2012. The Influence of Polysaccharides from the Roots of Achyranthes bidentata on Biochemical Parameters Related to Oxidative Stress Induced by Exhaustive Exercise of Rats. Journal of Animal and Veterinary Advances, 11: 4693-4696.