Authors : Bin Tong, Kaifeng Wu, Seiki Sasaki, Youji Muramatsu, Takeshi Ohta, Hiroyuki Kose and Takahisa Yamada
Abstract: Growth performance as well as marbling is the main breeding objectives in Japanese Black cattle, the major beef breed in Japan. The Myosin Heavy chain 1 (MYH1) gene is reported to encode an isoform of myosin heavy chain in type I fiber of skeletal muscle and has been previously shown to be located within genomic region of a quantitative trait locus for growth-related trait. The earlier study detected a Single Nucleotide Polymorphism (SNP), referred to as g.29850738G>A in the promoter regionof the MYH1 gene which exhibited significantly different allelic distribution between Japanese Black sires with extremely high predicted breeding value and the sires with extremely low one for Carcass Weight (CWT) and Rib Thickness (RT) in a preliminary study. In the present study, researchers analyzed the effect of the MYH1g.29850738G>A SNP genotypes on the growth-related carcass trait in Japanese Black beef cattle. The SNP was significantly associated with RT and marginally associated with CWT (p = 0.016 and 0.069, respectively) in experiment 1 using 101 Japanese Black sires. Further, a slight trend of significance for CWT and RT was observed for the SNP in experiment 2 using 745 paternal half-sib progeny steers from 2 sires homozygous for G allele at the g.29850738G>A in Japanese Black beef cattle. These findings suggest possible effect of the g.29850738G>A SNP on the growth-related trait in Japanese Black beef cattle. The MYH1 SNP may be useful for effective marker-assisted selection to increase the beef productivity in Japanese Black beef cattle.
Bin Tong, Kaifeng Wu, Seiki Sasaki, Youji Muramatsu, Takeshi Ohta, Hiroyuki Kose and Takahisa Yamada, 2014. Possible Association of Single Nucleotide Polymorphism in the Myosin Heavy Chain 1 Gene with Growth-Related Trait in Japanese Black Beef Cattle. Journal of Animal and Veterinary Advances, 13: 41-44.