Authors : Manuel Ignacio Balaguera, Jenny Paola Lis, Mercedes Gaitan, Amelec Viloria, Paula Vivana and Robayo Acuna
Abstract: In the present study an object oriented integrative modeling methodology is proposed for the construction of synthetic, computational models of bone-bone environment system that allow its simulation under in vivo conditions. The analytical mathematical approach to model and study ordinary materials will be outlined, indicating its limitations when dealing with biomaterials in physiological environments. The proposed object oriented integrative modeling will be explained emphasizing its advantages and possibilities. Finally, the architecture of the “in vivo” modeling and simulation software framework is shown, described and explained indicating further work based on this framework.
Manuel Ignacio Balaguera, Jenny Paola Lis, Mercedes Gaitan, Amelec Viloria, Paula Vivana and Robayo Acuna, 2017. Multiphysics Modeling for Bone Remodeling Simulation: A Methodological Framework. Journal of Engineering and Applied Sciences, 12: 2889-2896.