Authors : Nadher D. Radhy and Layth S. Jasim
Abstract: The adsorption of the miconazole drug from aqueous solution has been investigated using on hydroxyl propyl methyl cellulose-co-acrylic acid cross-linked as the adsorbents. Kinetics and thermodynamic studies were carried out to estimate the effect of equilibrium time, salts, temperature and pH value. The results of our study show that higher adsorption of the miconazole for this hydrogels. The adsorption process was studied as a function of temperatures (10, 20 and 30°C). The extents of drug adsorption on the hydrogels were results found it increases with increasing temperature, i.e., endothermic process. The values of the thermodynamic functions are calculated. Adsorption on hydrogels surfaces was examined as a function of pH. The adsorbed amount of drug on the surface was decreased as the pH increased. The results of the effect of the salt showed low adsorption capacity of the drug in the presence of sodium chloride.
Nadher D. Radhy and Layth S. Jasim, 2018. Adsorption and Kinetic Studies of Miconazole on Hydroxyl Propyl Methyl Cellulose-co-Acrylic Acid from Aqueous Solutions. Journal of Engineering and Applied Sciences, 13: 10517-10522.