Abstract: Higher speed, small area and more battery life are the prime factors in the fields of communication and information technologies. Complementary Metal Oxide Semiconductor (CMOS) technology uses presently for the physical network systems designs which have lot of limitations when it scaled to a nano-level, scientists and researchers have proposed several alternative technologies as solutions to replace CMOS by Quantum dot Cellular Automata (QCA) technology. QCA is one such promising alternative technology and possible solution for a perfect replacement of CMOS technology for designing digital circuits such as combinational and sequential circuit which have more occupation in the communication and computer systems. In this study, the sequential circuits D flip flop and shift register have been implemented with QCA technology. First, proposed a novel design of D Flip Flop (D-FF) and then the proposed D-FF has been utilized to implement the various shift registers (SISO, SIPO and PIPO). QCA based designs offers the features of significant reduction in design area, cell count and superior performance in speed as compared to the existing CMOS designs. QCA based clocked DFF offers an improvement of 45% in cell count, 65% design area and 60% minimizes the number of clock zones requirement.The proposed QCA design of clocked DFF with clear provides clear provide an improvement the cell count by 44, 40% in the design area and 40% clock zones reductionin relative to the existing designs. All these proposed designs are captured and simulated using a designing tool called QCA Designer 2.0.3.