Abstract: Since, transdermal delivery of therapeutics have been identified by scientific researchers as an alternative choice of drug administration, owing to its unique and tremendous benefit over conventional and oral administrations, special formulation that is capable of meeting up and overcoming its associated challenges is required. Nano-emulsion is one of the nano-technological formulations that have gained wide exposure as a novel drug delivery system that solves pharmaceutical challenges as well as improves dermal and transdermal drug delivery. The objective of this review is to create the basic understanding of the skin as an alternative transdermal delivery route while presenting nano-emulsions as a unique therapeutic vehicle. In this study, improvement in drug delivery application using nano-emulsions with particular attention to drug delivery transdermally is reviewed. The basic understanding and considerations in nano-emulsion generation including the required understanding of the skin as a possible transdermal drug delivery route is highlighted. The identity of nano-emulsions reflects a positive and successful application in the delivery of nano-therapeutics to the systemic circulation through the skin.
O.B. Akinsipo, Samson Oluwagbemiga Alayande, Deepshikha Pande Katare and E.O. Dare, 2020. Nanoemulsion: A Promising and Novel Nanotherapeutic Vehicle for Transdermal Drug Delivery Application. Journal of Engineering and Applied Sciences, 15: 3214-3225.