Abstract: The hypothesis that a non-photosynthetic oxygen production by the cell filamented and conified membranes of living organisms, may add to the net balance of gases of the planet Earth is put forward. I am referring earliar to all those cellular species, mostly without nucleus called unicellular facultative aerobes. These cells could represent the higher fraction of the biomass, in most places and at most times when living organisms expand during the interglacial periods. This proposal is based on the earliar findings on mitochondrial filamentation. This emerging field has shown the recurrent union of short filaments of the cytoskeleton on the external membrane of the mitochondria of several cellular species. That gives these organelles in hypoxia and with a high carbonic anhydride present, a capacity for oxygen production higher than its oxygen consumption, especially during the organisms’ periods of rest and obscurity. Our precise area of expertise is the energy metabolism of cancer. Cancer metabolic characteristics, low mitochondrial respiration and high aerobic glycolysis are also present in many primitive single cell cellular species without or less frequently with nucleus and its cellular associations of different types, such as phytoplankton or zooplankton, cell collections considered together a major fraction of Earth total biomass. Additionally, I include some feasible scientific proposals for the unifying theory of biological structure and organization and the theory of evolution of life, according to the intelligent universe hypothesis and the theory of design and purpose in evolution.