Abstract: Mining has been reported to deplete the organic matter content and nutrients of soil through erosion and decomposition. The effect of mining on organic matter content and nutrients of soil in the iron ore deposit area of Itakpe, Kogi state of Nigeria was investigated. The study involves the determination of organic matter content and nutrients content viz nitrogen, potasium and phosphorous of some soil in order to have a baseline for assessing the impact of iron ore mining in future. Soil samples were collected, predigested and analysed using appropriate standard methods. The results revealed that soil of the mined sites have lower organic matter content and nutrients than unmined site. Likely, consequences of this discovery on the livelihood of residents of the area are discussed. Useful suggestions are made on building up of the soil organic matter content and nutrients for agricultural activities.