Authors : Mohammed Noori Al-Dujaili, Laith Abdulhussein Al-dabbagh and Mohammad Nassar Karkosh
Abstract: One of the most killer and common silent disease worldwide is Coronary Artery Disease (CAD), contributing high morbidity and mortality. The approximate of Epicardial Adipose Tissue (EAT) to the coronary arteries plays an important role within the pathogenesis of CAD previous studies proved that coronary artery disease had been recommended to be directly related to the Epicardial adipose tissue thickness. The purpose of this study is to assess the accuracy of epicardial adipose tissues thickness in predicting coronary artery stenosis. A cross-sectional study carried out at Al-Sader teaching medical city during the period from the first of January to the 15th of October 2014 included 80 with coronary artery diseases underwent cardiac catheterization regardless their age or gender. Patients with valvular hear diseases or poor echocardiographic window were excluded. ECG, the Echocardiographic examination were performed in all patients. Three cut-off points of thickness were used, according to the measurement point; on RV Apex = 8 mm, RV free wall those = 10 mm and right ventricle outlet tract = 13 mm which are considered abnormal accumulation of EAT. The data were analyzed using SPSS version 21 and appropriate statistical tests were applied. The mean of the patients age was 52.1±9.8 (range: 25-77) years, more than two thirds (70%) of the patients were males. Smokers represented (25%), History of hypertension (17.5%), diabetes mellitus(10%). The mean EAT thickness at RV apex was 3.62±0.46 mm at RV free wall was 3.79±0.42 and at the RV outlet tract it was 3.9±0.45 mm, the mean EAT thickness was higher in younger patients and decreased with the advancing age, male gender, smoking, history of hypertension and history of diabetes are associated with larger mean EAT thickness. Because of this EAT thickness is a great predictor of CAD with sufficient sensitivity, specificity and accuracy. Using the echocardiographic assessment of Epicardial adipose tissue thickness can be a great assistance for clinicians to detect the people at risk.
Mohammed Noori Al-Dujaili, Laith Abdulhussein Al-dabbagh and Mohammad Nassar Karkosh, 2016. Assessment of Epicardial Adipose Tissue Thickness in Patient with Coronary Artery Disease. Research Journal of Medical Sciences, 10: 557-564.