Authors : Rassim A. Kerimov, Bakhytzhan D. Seksenbayev, Oleg V. Galimov, Bekaydar K. Nurmashev and Murat E. Zhanteyev
Abstract: Colorectal cancer keeps an upward incidence trend worldwide. Many studies show that colon cancer is preventable disease in most cases: 70% of them might be avoided by lifestyle and diet changes. Despite the globalization processes, ethnic mode of life at a certain extent forms lifestyle and nutrition habits of the Kazakhstan population. Disparities in people traditions may be reflected in the features of colorectal cancer development among different ethnic groups of the studied areas. The aim of the study was to assess associations between colorectal cancer and major ethnic groups residing in Kazakhstan. This was a retrospective study in which we analyzed all primary cases of colorectal cancer registered in 2013 year. All records were provided by the regional oncology centers in 4 regions of the republic. Eventually, a cohort of 709 cases was formed. Each record of the disease was analyzed in terms of ethnicity, age, gender, disease stage and tumor location. A significant association between colorectal cancer and ethnicities was found in the patient group (X2(2) = 213.5, p<0.001): in Russians, the disease was registered 1.9 time as many as it was expected. No (2) associations between colorectal cancer and tumor location were found for any ethnic group. The study suggests a significant association between the disease and the ethnic groups residing in Kazakhstan. Nutrition and lifestyle tendencies might play rather important role in this matter than any biological signs. We suggest a case-control study should be conducted for further investigation of revealed relationship.
Rassim A. Kerimov, Bakhytzhan D. Seksenbayev, Oleg V. Galimov, Bekaydar K. Nurmashev and Murat E. Zhanteyev, 2017. Colorectal Cancer and Ethnic Groups in Kazakhstan. A Retrospective Study of 709 Cases. Research Journal of Medical Sciences, 11: 114-118.