Authors : L.S. Yermukhanova, A.N. Zhexenova, G.N. Izimbergenova, M.N. Turebaev, A.U. Bekbauova, E.B. Zhumabekov and M.U. Umbetov
Abstract: Aim of the research is to investigate immunodeficiency of people, residing in the oil-producing region and determine the contribution of environmental factors to the frequency of allergic diseases in the study area. By the results of testing among 2789 of studied residents were taken 424 people with Immuno Deficiency Syndrome (IDS) of 2 and 3 stages which were held 2 level immunological tests. For the assessment of cellular immunity sets used monoclonal and polyclonal antibodies for human leukocyte antigens differentiated by immunofluorescence. To assess the reliability of the results and determine the level of contribution of environmental factors in the incidence of allergic diseases in the study area, analysis of variance was conducted. Toassess the connection degree ofmorbidity of allergosiseswith air pollutioncorrelation analysis was conducted. Quality of diseases as pollinoz (F = 7.5, dt = 4.1 and F 0.5 p<0.05) bronchial asthma (F = 3.5, dt = 5.1 and F = 0.5 = 3.8 p<0.05) dermatitis (F = 9.7, dt = 1.2 and F 0.1 = 13.5 p<0.001) and other allergic diseases (F = 2.5, dt = 2.1 and F = 0.5 p<0.05). Thus, we claim with the confidence that the combined effect of air chemical factors leads to the population of immunodeficient states against witch increases the risk of allergic diseases and other immunodeficiencies.
L.S. Yermukhanova, A.N. Zhexenova, G.N. Izimbergenova, M.N. Turebaev, A.U. Bekbauova, E.B. Zhumabekov and M.U. Umbetov, 2017. Immunodeficiency States in Persons Residing in the Oil-Producing Regions of Kazakhstan. Research Journal of Medical Sciences, 11: 16-18.