Abstract: Balinese society is a religious society, obedient and submissive to the traditional values and traditions, both of these factors have been able to maintain the socio-cultural values that grow and develop in accordance with the mechanisms of society and development of the era. The people who choose business venture as a way to improve the quality of life, it absolutely necessary to religion/dharma. As for signs Balinese Hindu community in business are the values of local wisdom that comes from Hinduism, namely: “Apang pada payu/Mangda sami durus”, “bani meli-bani ngadep” or often termed as “manis batu”. In the sense of living together, for example, in trade competition dare to buy also dare to sell, it’s very different from the principle of economy that profit-oriented. The purpose of this study was to determine the public perception to the implementation of business ethics based on local knowledge that not only profit oriented but with an integral and holistic approach to the present and the future. In this study, the research focus is located in the city of Denpasar. Business ethics which is the focus of this research is ethics-based business of local wisdom in Denpasar namely: application of the concept “Mangda sami durus/pang pada payu”, “Bani meli bani ngadep/Manis batu”. Sources of data are primary data and secondary data. Data collection technique uses in-depth interview, observation and documentation. Technique of validity data test in this study uses triangulation technique while data analysis technique that used in this research is descriptive qualitative data analysis techniques. Based on the results of research conducted by the informer was found that the public has a positive perception to the application of business ethics based on local knowledge in Denpasar City.