Authors : Maryam Esmaeilzadeh , Majid Maleki and Fereidoun Noohi
Abstract: The purpose of this study was to quantitate the degree of left-to-right shunt in patients with 2°ASD by PISA method in comparison with continuity equation. The PISA method has been used extensively in patients with valvular regurgitation and stenosis for quantitative measurement of regurgitant severity and valve area. But its use in patients with left-to-right shunts including ASD has not been evaluated extensively. We studied 48 consecutive patients with 2° ASD (mean age: 32.5+-4 years; range: 18-54 years). Left-to-Right shunting was quantified by continuity equation and PISA methods. The defect size was between 12-40 mm (mean: 26+- 6). QP/QS by continuity equation was between 1.7-4.5/1 (mean: 2.91) and by PISA method was between 1.6-4.8/1 (mean: 2.92), [r = 0.92, PV= 0.0001]. There was no significant difference between the degree of shunt estimated by continuity equation and PISA method in terms of the defect size and the degree of shunt (PV = 0.179). The PISA method could be as an accurate alternative method of continuity equation for quantitation of the degree of shunt flow in patients with 2°ASD.
Maryam Esmaeilzadeh , Majid Maleki and Fereidoun Noohi , 2006. Quantification of Left-to-Right Shunt in 2°ASD by PISA Method . The Cardiology, 2: 19-22.