Research Journal of Biological Sciences

Year: 2009
Volume: 4
Issue: 7
Page No. 777 - 784

Attenuation of Cisplatin-Induced Hepatotoxicity in Rats Using Zerumbone

Authors : Mohamed Yousif Ibrahim, Ahmad Bustamam Abdul, Siddig Ibrahim Abdel Wahab, Manal Mohammed Elhassan, Adel Sharaf Alzubairi and M.M. Syam

References

Abdul, A.B.H., A.S. Al-Zubairi, N.D. Tailan, S.I. Abdel-Wahab, Z.N.M. Zain, S. Ruslay and M.M. Syam, 2008. Anticancer activity of natural compound (Zerumbone) extracted from Zingiber zerumbet in human hela cervical cancer cells. Int. J. Pharmacol., 4: 160-168.
CrossRef  |  Direct Link  |  

Aggarwal, B.B. and S. Shishodia, 2006. Molecular targets of dietary agents for prevention and therapy of cancer. Biochem. Pharmacol., 71: 1397-1421.
CrossRef  |  PubMed  |  Direct Link  |  

Ali, B.H., M. Al-Moundhri, M. Tageldin, I.S. Al-Husseini, M.A. Mansour, A. Nemmar and M.O. Tanira, 2006. Ontogenic aspects of Cisplatin 10 mg kg-1 platin-induced nephrotoxicity in rats. Food Chem. Toxicol., 46: 3355-3359.
CrossRef  |  

Ali, B.H., M. Al-Moundhri, M. Tageldin, I.S. Al-Husseini, M.A. Mansour, A. Nemmar and M.O. Tanira, 2006. Ontogenic aspects of cisplatin-induced nephrotoxicity in rats. Food Chem. Toxicol., 46: 3355-3359.
CrossRef  |  PubMed  |  Direct Link  |  

Ali, B.H., M.S. Al-Moundhri, M. Tag-Eldin, A. Nemmar and M.O. Tanira, 2007. The ameliorative effect of cysteine prodrug L-2-oxothiazolidine-4-carboxylic acid on Cisplatin 10 mg kg-1 platin-induced nephrotoxicity in rats. Fundam. Clin. Pharmacol., 21: 547-553.
PubMed  |  

Aykac, G., M. Uysal, A.S. Yalcin, N. Kocak-Toker, A. Sivas and H. Oz, 1985. The effect of chronic ethanol ingestion on hepatic lipid peroxide, glutathione peroxidase and glutathione transferase in rats. Toxicology, 36: 71-76.
PubMed  |  

Blakley, B.W., J.I. Cohen, N.D. Doolittle, L.L. Muldoon, K.C. Campbell and D.T. Dickey, 2001. Strategies for prevention of toxicity caused by platinum-based chemotherapy. Laryngoscope, 112: 1997-2001.
PubMed  |  

Chien, T.Y., L.G. Chen, C.J. Lee, F.Y. Lee and C.C. Wang, 2008. Anti-inflammatory constituents of Zingiber zerumbet. Food Chem., 110: 584-589.
CrossRef  |  

Ekborn, A., A. Lindberg, G. Laurell, I. Wallin, S. Eksborg and H. Ehrsson, 2003. Ototoxicity, nephrotoxicity and pharmacokinetics of Cisplatin 10 mg kg-1 platin and its monohydrated complex in the guinea pig. Cancer Chemother Pharmacol., 51: 36-42.
PubMed  |  

Fetoni, A.R., B. Sergi, A. Ferraresi, G. Paludetti and D. Troiani, 2004. Protective effects of α-tocopherol and tiopronin against Cisplatin 10 mg kg-1 platin-induced ototoxicity. Acta Otolaryngol., 124: 421-426.
PubMed  |  

Hoffman, A., L.M. Spetner and M. Burke, 2002. Redox-regulated mechanism may account for zerumbone`s ability to suppress cancer-cell proliferation. Carcinogenesis, 23: 1961-1961.
PubMed  |  

Hong, K.O., J.K. Hwang, K.K. Park and S.H. Kim, 2005. Phosphorylation of c-Jun N-terminal Kinases (JNKs) is involved in the preventive effect of xanthorrhizol on cisplatin-induced hepatotoxicity. Arch. Toxicol., 79: 231-236.
CrossRef  |  PubMed  |  Direct Link  |  

Iraz, M., E. Ozerol, M. Gulec, S. Tasdemir, N. Idiz and E. Fadillioglu, 2006. Protective effect of caffeic acid phenethyl ester administration on Cisplatin 10 mg kg-1 platin-induced oxidative damage to liver in rat. Cell. Biochem. Funct., 24: 357-361.
PubMed  |  

Iraz, M., M.T. Kalcioglu, A. Kizilay and E. Karatas, 2005. Amino guanidine prevents ototoxicity induced by Cisplatin 10 mg kg-1 platin in rats. Ann. Clin. Lab. Sci., 35: 329-335.
PubMed  |  

Iseri, S., F. Ercan, N. Gedik, M. Yuksel and I. Alican, 2007. Simvastatin attenuates cisplatin-induced kidney and liver damage in rats. Toxicology, 230: 256-264.
CrossRef  |  PubMed  |  Direct Link  |  

Kalkanis, J.G., C. Whitworth and L.P. Rybak, 2004. Vitamin E reduces Cisplatin 10 mg kg-1 platin ototoxicity. Laryngoscope, 114: 538-542.

Kasparkova, J., O. Delalande, M. Stros, M.A. Elizondo-Riojas, M. Vojtiskova, J. Kozelka and V. Brabec, 2004. Recognition of DNA interstrand cross-link of antitumor Cisplatin 10 mg kg-1 platin by HMGB1 protein. Biochemistry, 42: 1234-1244.
PubMed  |  

Kim, S.H., K.O. Hong, J.K. Hwang and K.K. Park, 2005. Xanthorrhizol has a potential to attenuate the high dose Cisplatin 10 mg kg-1 platin-induced nephrotoxicity in mice. Food Chem. Toxicol., 43: 117-122.
CrossRef  |  

Koc, A., M. Duru, H. Ciralik, R. Akcan and S. Sogut, 2005. Protective agent, erdosteine, against Cisplatin 10 mg kg-1 platin-induced hepatic oxidant injury in rats. Mol. Cell. Biochem., 278: 79-84.
PubMed  |  

Leitao, D.J. and B.W. Blakley, 2003. Quantification of sodium thiosulphate protection on Cisplatin 10 mg kg-1 platin-induced toxicities. J. Otolaryngol., 32: 146-150.
PubMed  |  

Leonetti, C., A. Biroccio, C. Gabellini, M. Scarsella, V. Maresca and E. Flori, 2003. Alpha-tocopherol protects against Cisplatin 10 mg kg-1 platin-induced toxicity without interfering with antitumor efficacy. Int. J. Cancer, 104: 243-250.
PubMed  |  

Liao, Y., X. Lu, C. Lu, G. Li, Y. Jin and H. Tang, 2008. Selection of agents for prevention of cisplatin-induced hepatotoxicity. Pharmacol. Res., 57: 125-131.
CrossRef  |  PubMed  |  Direct Link  |  

Liao, Y.J., H. Tang and Y.P. Jin, 2004. Study of toxic effects on hearing, kidney and liver of mice induced by anticancer agent of Cisplatin 10 mg kg-1 platin and their mechanisms. Chin. Pharmacol. Bull., 20: 82-85.
Direct Link  |  

Liu, J., Y. Liu, S.S. Habeebu and C.D. Klaassen, 1998. Metallothionein (MT)-null mice are sensitive to cisplatin-induced hepatotoxicity. Toxicol. Applied Pharmacol., 149: 24-31.
PubMed  |  

Lu, Y. and A.I. Cederbaum, 2006. Cisplatin-induced hepatotoxicity is enhanced by elevated expression of cytochrome P450 2E1. Toxicol. Sci., 89: 515-523.
CrossRef  |  PubMed  |  Direct Link  |  

Mansour, H.H., H.F. Hafez and N.M. Fahmy, 2006. Silymarin modulates Cisplatin-induced oxidative stress and hepatotoxicity in rats. J. Biochem. Mol. Biol., 39: 656-661.
PubMed  |  Direct Link  |  

Murakami, A., R. Hayashi, T. Tanaka, K.H. Kwon, H. Ohigashi and R. Safitri, 2003. Suppression of dextran sodium sulfate-induced colitis in mice by zerumbone, a subtropical ginger sesquiterpene and nimesulide: Separately and in combination. Biochem. Pharmacol., 66: 1253-1261.
CrossRef  |  PubMed  |  Direct Link  |  

Nowak, G., 2002. Protein kinase C-alpha and ERK1/2 mediate mitochondrial dysfunction, decreases in active Na-+ transport and Cisplatin 10 mg kg-1 platin-induced apoptosis in renal cells. J. Biol. Chem., 227: 43377-43388.
PubMed  |  

Pratibha, R., R. Sameer, P.V. Rataboli, D.A. Bhiwgade and C.Y. Dhume, 2006. Enzymatic studies of Cisplatin 10 mg kg-1 platin induced oxidative stress in hepatic tissue of rats. Eur. J. Pharmacol., 532: 290-293.
PubMed  |  

Rabik, C.A. and M.E. Dolan, 2007. Molecular mechanisms of resistance and toxicity associated with platinating agents. Cancer Treatment Rev., 33: 9-23.
CrossRef  |  PubMed  |  Direct Link  |  

Ramesh, G. and W.B. Reeves, 2002. TNF-alpha mediates chemokine and cytokine expression and renal injury in Cisplatin 10 mg kg-1 platin nephrotoxicity. J. Clin. Invest., 110: 835-842.
PubMed  |  

Ravi, R.S., S.M. Somini and L.P. Rybak, 1995. Mechanism of cisplatin ototoxicity, antioxidant system. Pharmacol. Toxicol., 76: 386-394.
PubMed  |  

Sakinah, S.A.S., S.T. Handayani and L.P.A. Hawariah, 2007. Zerumbone induced apoptosis in liver caner cells via modulation of Bax/Bcl-2 ratio. Cancer Cell Int., 7: 4-4.
CrossRef  |  PubMed  |  

Surh, Y.J., 1999. Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances. Mutat. Res., 428: 305-327.
Direct Link  |  

Takada, Y., A. Murakami and B.B. Aggarwal, 2005. Zerumbone abolishes NF-κB and IκBα kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis and downregulation of invasion. Oncogene, 24: 6957-6969.
CrossRef  |  PubMed  |  Direct Link  |  

Townsend, D.M. and M.H. Hanigan, 2002. Inhibition of gamma-glutamyl transpeptidase or cysteine S-conjugate beta-lyase activity blocks the nephrotoxicity of Cisplatin 10 mg kg-1 platin in mice. J. Pharmacol. Exp. Ther., 300: 142-148.

Visarus, T.M., D.A. Putt, J.M. Schare, D.M. Pegouske and L.H. Lash, 1996. Pathways of glutathione metabolism and transport in isolated proximal tubular cells from rat kidney. Biochem. Pharmacol., 52: 259-272.
PubMed  |  

Weijl, N.I., T.J. Elsendoorn, E.G. Lentjes, G.D. Hopman and A. Wipkink-Bakker et al., 2004. Supplementation with antioxidant micronutrients and chemotherapy-induced toxicity in cancer patients treated with Cisplatin 10 mg kg-1 platin-based chemotherapy: A randomised, double-blind, place-bocontrolled study. Eur. J. Cancer, 40: 1713-1723.
PubMed  |  

Xiao, T., S. Choudhary, W. Zhang, N.H. Ansari and A. Salahudeen, 2003. Possible involvement of oxidative stress in Cisplatin 10 mg kg-1 platin-induced apoptosis in LLC-PK1 cells. J. Toxicol. Environ. Health A, 66: 469-479.
PubMed  |  

Yao, X., K. Panichpisal, N. Kurtzman and K. Nugent, 2007. Cisplatin 10 mg kg-1 platin nephrotoxicity: A review. Am. J. Med. Sci., 334: 115-124.
PubMed  |  

Yüce, A., A. Ateşşahin, A.O. Çeribaşı and M. Aksakal, 2007. Ellagic acid prevents cisplatin-induced oxidative stress in liver and heart tissue of rats. Basic Clin. Pharmacol. Toxicol., 101: 345-349.
CrossRef  |  PubMed  |  Direct Link  |  

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