Abstract: This study characterized and investigated optimality of Generalized gradient vector flow active contours as a suitable boundary mapping technique for Chromosome spread images having variability in shape and size. Boundary mapping using generalized gradient vector flow active contours is done on chromosome spread images and it is found that a unique set of parameter values for the technique is required for boundary mapping every chromosome image. Characterization studies have shown that an optimal range of values exists for each parameter within which good boundary mapping results can be obtained for various chromosomes in similar class of images. Statistical testing validates the experimental results.
A.Prabhu Britto and G.Ravindran , 2005. Characterization of Discrete Cosine Transform Based Generalized Gradient Vector Flow Active Contours for Boundary Mapping of Chromosome Spread Images and Investigations . Asian Journal of Information Technology, 4: 971-977.