Authors : G. Senthilvel , M. Jegadeesan , Anoop Austin , P. Thirugnanasambantham , E. Mayisvren , M. Balasubramanian , N. Narayanan and S. Viswanathan
Abstract: Diarun plus was evaluated for its therapeutic antihyperglycemic activity in streptozotocin-induced diabetes in animal models. It was effective in controlling hyperglycemic status in rats and mice. The drug (500 mg/kg) showed significant antidiabetic property as judged by serum glucose levels. However, it did not significantly influence the levels of serum insulin in both diabetic and normoglycemic rats. This is a promising drug to develop standardized phytomedicine for diabetes mellitus. The findings suggest that it can be considered as a therapeutic agent, wherever elevated glycemic status is observed.
G. Senthilvel , M. Jegadeesan , Anoop Austin , P. Thirugnanasambantham , E. Mayisvren , M. Balasubramanian , N. Narayanan and S. Viswanathan , 2006. Effect of a Polyherbal Formulation (Diarun plus) on Streptozotocin Induced Experimental Diabetes. International Journal of Tropical Medicine, 1: 88-92.