Abstract: This experiment was conducted to determine the nutrient composition of processed and stored abattoir waste (AW); a scrapping of the papillae layer of rumen of slaughtered cattle in Nigeria. Effect of diets containing increasing levels of abattoir waste on feed acceptability, haematological and serological indices and internal organ weights of West African Dwarf (WAD) goats were studied. Chemical composition analysis revealed that oven dried sample contained higher Crude Protein (CP), Dry Matter (DM) and Gross Energy (GE) than sun cured sample. (67.70, 91.52 and 3.95 Mcal/kg vs 60.49, 83 45 and 3.54 Mcal/kg). DM contents of oven dried and sun cured AW samples were not stable during storage for 6 weeks in a silo. An increase was observed in CP content of both samples while EE contents decreased during storage. Concentrate diets were formulated such that 0 (A), 35 (B), 70 (C) and 100% (D) of Soy Bean Meal (SBM); a conventional but expensive feedstuff, was replaced with sun cured AW. All diets were approximately isonitrogenous (161-171 g CP kg^-1 DM). These diets were fed along with grass ad libitum to 16 growing WAD bucks with mean body weights of 6�1.5 kg in a completely randomized design for 28 days to determine treatment effect on acceptability of feed, hematological and serological profiles and internal organs weights of experimental animals. No significant difference was observed in total intake, however, goats preferred concentrate diets to grass as revealed by DM concentrate intake ranging from 91.31 to 92.21% of total intake. The mean serum metabolite�s indices showed the value of total protein levels of animals on diets A, C and D as 6.40, 6.30 and 6. 33 g 100 mL, respectively. Dietary affect on serum cholesterol and albumin: globulin ratios were significant (p<0.05). Variations observed in haematological indices due to dietary treatments were also significant. Spleen weights were similar (p>0.05) for goats on diet B, C and D, but lower in animals on diet A. Animals on diets C and D had significantly higher heart weights. It could be deducted that replacement of SBM with above 35% might be support good performance and production in good nutrition.