Abstract: Forty batches of anthrax spore vaccine were produced by bioreactor and by Roux flask, 20 batches were obtained from each system. The number of doses produced in the flask system was found 10 times more than those obtained by the bioreactor. It is recommended to continue producing this vaccine by the Roux flask while research will go on to improve suitable conditions in the fermenter in order to obtain high doses and to avoid the drawbacks of the flask system.
Abbas Mohamed Ahmed , N.T. Mekki , Muna O. Elhaj and Sarah Mohamed Abusalab , 2006. A Comparative Study on The Production of Concentrates of Anthrax Live Spore Vaccine in Roux Flasks and in Fermenter. Journal of Animal and Veterinary Advances, 5: 92-95.