Abstract: The aim of this study was to investigate possible changes in the serum paraoxonase-1 (PON1) activity at the prepartum and postpartum stages in Holstein cows and to examine the relation between PON1 activity and dystocia. The 2nd objective of this study was to describe prepartum and postpartum serum concentrations of other relevant blood parameters and their associations with dystocia risk. Initially, 200 Holstein and 65 Holstein x Black home crosbreed cows, aged 3-8 year, were selected for this study. Samples were taken both in the 7th month of pregnancy and within the first 15 min postpartum. At the end of pregnancy, the cows were divided into two groups according to the type of birth: Difficult labour and normal labour. PON1 activities measured in the prepartum samples were significantly higher than in postpartum samples from cows which had normal or difficult labour. Although, PON1 activity from cows with dystocia was lower both pre-and postpartum, this difference did not reach statistical significance. Furthermore, there was a tendency to decreased PON1 activities in the case of absolute birth weight and twins. Evaluation of cholesterol, HDL-C, LDL-C, albumin, globulin and alkaline phosphatase levels does not appear to be useful in the assessment of dystocia. However, increased serum creatine kinase and creatine kinase isoenzyme MB may be a parameter which could be used in diagnosing dytocia in pregnancy.
Servet Bademkiran , Beran Yokus , Dilek Ulker Cakir , Mehmet Hanifi Durak and Dogan Kurt , 2008. Serum Paraoxonase-1 Activity in Dairy Cattle and its Association with Dystocia. Journal of Animal and Veterinary Advances, 7: 1184-1189.