Authors : N. Hadjipour , M. Marjani , R. Sedaghat and S.H. Marjanmehr
Abstract: The chromic catgut sutures are the most common suture materials in surgical operations. The purpose of this in vivo study was to histopathologically evaluate the inflammatory reactions incited by five different kinds of catgut suture materials. Five different catgut suture materials from five companies were compared with each other. Thirty five adult New Zealand white rabbits, fed a solid diet, were divided into five groups of five rabbits each. Five kinds of catgut suture materials were implanted into the back and thigh muscles. After 1, 3, 7, 14 and 28 days, the animals were sacrificed and the suture materials plus the subcutaneous and muscle tissues were removed from the implanted areas. Results revealed that there were significant differences between the granolomatous inflammatory reactions of used suture materials (p<0.05). Statistical analysis to compare each two suture materials were performed and in the most of them the differences were significant. Furthermore, statistical analysis were performed to compare all of the 5 suture materials. As a result, it can be considered that because raw materials of these sutures which are from the intestine of particular animals are different, the pathological effects of these materials are variable and this matter is not matched with the rules of standards about the materials being used in medicine and veterinary medicine. So, these suture materials had better not be recommended anymore.
N. Hadjipour , M. Marjani , R. Sedaghat and S.H. Marjanmehr , 2008. Histopathological Absorption Trend Comparison Between Chromic Catgut Suture Materials Produced by Different Companies in Rabbits. Journal of Animal and Veterinary Advances, 7: 1341-1344.