Authors : Kaizhou Xie, Huisheng Guo, Longfei Jia, Yuping Huang, Xing Xie, Yilin Yao, Dong Xu, Xuesheng Chen, Guojun Dai, Xiaojie Zhang, Yingying Sun, Jinyu Wang and Zongping Liu
Abstract: Eggs of laying hens were used to study residue depletion of Florfenicol (FF) and its metabolite Florfenicol Amine (FFA) after oral dose (25.0, 50.0 and 100.0 mg kg-1 body weight), once daily for 5 days. The residues were determined by High Performance Liquid Chromatography with Fluorescence Detection (HPLC-FLD). The maximum concentration of FF was all detected at 1 day in the albumen, yolk and whole eggs; the maximum concentration of FFA was detected at 1 day in the albumen and whole eggs, at 3 days in the yolk after cessation of medication. After oral administration of 100.0 mg kg-1, concentrations of FF and FFA were all below the LODs (1.5 μg kg-1 for FF and 0.5 μg kg-1 for FFA) at 7 days for the albumen, 11 days for yolk and 10 days for whole egg after cessation of medication.
Kaizhou Xie, Huisheng Guo, Longfei Jia, Yuping Huang, Xing Xie, Yilin Yao, Dong Xu, Xuesheng Chen, Guojun Dai, Xiaojie Zhang, Yingying Sun, Jinyu Wang and Zongping Liu, 2012. Residue Depletion of Florfenicol and its Metabolite Florfenicol Amine in Eggs. Journal of Animal and Veterinary Advances, 11: 1012-1017.