Authors : Wei Wang, Xiao-Mao Guo, Jian Wang and Song-Jia Lai
Abstract: Meat products normally contain low omega-3 fatty acids and high ratio of n-6/n-3 fatty acids may contribute to the prevalence of many diseases. In order to obtained in such beef with high levels of omega-3 fatty acids will be more healthy to meet people’s diet, researchers generated the fat-1 transgenic simmental crossbred cattle expressing the Caenorhabditis elegans c fat-1 gene encoding an omega-3 fatty acid desaturase that converts omega-6 to omega-3 fatty acids and the gene is absent in mammals. In this study, researchers successful product the embryo of fat-1 transgenic simmental crossbred cattle using OSM. The results of Western Blotting and fluoroscopic examination have proved that the fat-1 gene has been into genome of clone embryo and translated into proteins which could be used to embryo transfer.
Wei Wang, Xiao-Mao Guo, Jian Wang and Song-Jia Lai, 2012. Product Fat-1 Transgenic Simmental Crossbred Cattle Endogenously Synthesizing Omega-3 Polyunsaturated Fatty Acids Using OSM. Journal of Animal and Veterinary Advances, 11: 1041-1045.