Authors : Mihreteab Bekele, Tilahun Gessesse, Yisehak Kechero and Mesele Abera
Abstract: Experimental study was conducted to investigate in-vitro anthelmintic activities of condensed tannins on egg hatch ability and larval development inhibition of sheep Hemonchus contortus. In view of that, three indigenous medicinal plants: Rhus glutinosa, Syzygium guineensa and Alpizia gumifera were selected based on their relatively high content of condensed tannins and their aqueous acetone extraction was used for egg hatchability and larval development inhibition assays. The results showed that various concentrations of the extracts of all three condensed tannins demonstrated statistically significant (p<0.05) dose dependent inhibition of both egg hatchability and larval development. According to ED50 and ED90 values, the condensed tannin inhibiting egg hatching and larval development most potently was Rhus glutinosa followed in descending order of activity by Syzygium guineensa and Alpizia gumifera. Finally, our work suggests that condensed tannins might be recommended as one of the options for the control of Hemonchus contortus of sheep.
Mihreteab Bekele, Tilahun Gessesse, Yisehak Kechero and Mesele Abera, 2016. In-vitro Antihelmintic Activity of Condensed Tannins from Rhus Glutinosa, Syzygium Guineensa and Alpizia gumifera a Gainst Sheep Hemonchus contortus. Journal of Animal and Veterinary Advances, 15: 75-82.