Abstract: The study is to identify a new method for medical information systems to improve physical function after surgery for ovarian cancer. Experimental group investigated 61 people who were consisted of members by the application of mediating technology while the normal members of 61 people were consisted of people without mediating technology. The X²-test was used for the examination of the general variables between two groups. The t-test was performed the difference of life habits by the application of medical information systems. The results are as follows. Firstly, male with 47.5% in the experimental group showed a higher rate than male with 42.6% in the normal people. While female of 52.5% in the test groupwas observed less than female with 57.4% in the normal group. Secondly, for vitamin intake, the mean point (79.51±0.69) of the group which have eaten vitamin in the post-test by mediating technology system were statistically significantly higher than the mean point (51.84±2.93) of the group in the pre-testby the application of medical information systems (t = -5.17, p = 0.000). Thirdly, the data achieved a significantly higher rate in the group observed than the normal group, even the days passed 20 days by the application of medical information systems. Therefore, the study conducted to evaluate the effectiveness of medical information systems. This impact of medical information system will have a technique on prevention of ovarian cancer.