Authors : Kareem Hussein Jwad, Nehia Neama Hussein, Buthenia Abd-Alhamza, Ahmed A. Al-Amiery and Ayad F. Alkaim
Abstract: This study aimed to determinate the antibacterial activity and cytotoxic effects (Fe3O4 NPs). Antimicrobial activity against pathogenic microbes which obviously indicates that Fe3O4 NPs are considered an valuable antimicrobial agents. The (G +ve bacteria) S. aureus were more susceptible to iron oxide nanoparticles when compared to the E. coli and P. aeruginosa (G -ve bacteria). Results indicate that inhibitory activity of iron oxide nanoparticles increases with increase of the Fe3O4 NPs concentrations. Fe3O4 NPs was not effect on every cells but through an suitable magnetic field of iron oxide as for the detection of the toxicity of nanoparticles it was observed that it had toxicity to red blood cells through the complete haemolysis. The current study concluded the Fe3O4 NPs can effects on the inflammatory response that which cause the oxidative stress and may negatively affect the cellular function and Fe3O4 NPs in high concentrations have a hemagglutinated.
Kareem Hussein Jwad, Nehia Neama Hussein, Buthenia Abd-Alhamza, Ahmed A. Al-Amiery and Ayad F. Alkaim, 2018. Study and Synthesis of Fe O Nanoparticles Prepared by Laser 3 4 Ablation and its Biomedical Application. Journal of Engineering and Applied Sciences, 13: 10633-10638.