Abstract: An innovative project "Healthy cities without tobacco" was implemented to ensure the implementation of the regulations of the Federal Law No. 15-FZ at the regional and city level regarding the restriction of the spread of tobacco, the ban on tobacco smoking in public places, state and social institutions in the cities of the Russian Federation. This study presents the experience of implementing this project. The project is aimed at increasing interaction with authorities, controlling structures and active community to ensure tobacco smoking restriction in public places and institutions in 22 cities of the association of "healthy cities, districts and villages" as well as the development of local strategies for tobacco control. There are outcomes of the project: effective collaboration on control tobacco smoking on municipal level, realistic action plan on preventive measures against tobacco was created and implemented.