Authors : Nurul Hazwani Hanib, Fazlena Hamzah, Zarina Omar and Istikamah Subuki
Abstract: Simulated Body Fluid (SBF) solution has been used in biomimetic apatite coating. In some cases, the apatite formation on the metallic surface may take up to 4 weeks in SBF solution. Increasing the concentration of SBF seems to work in shortening the period of apatite formation yet the high concentration of unstable SBF solution is not easy to handle. Another potential solution that mimics human blood plasma to hasten the apatite formation is Dulbecco’s Phosphate Buffered Saline. The aim of this research was to investigate the formation of apatite in Dulbecco’s Phosphate Buffered Saline (DPBS) solution modified with CaCl2 and MgCl2 on the surface of alkali treated Ti6Al4V. The bioactive surface on Ti6Al4V was prepared by alkali etching using 5M NaOH and 5M KOH and consolidated by heat treatment at 500 and 600°C The morphology structure, phase changes, wettability and chemical composition of apatite coating were characterised. The results demonstrated that apatite coating in globular rosette-like shape was formed on the surface treated with NaOH and subsequently heat-treated at 500°C within 3 days of immersion time in DPBS solution. Significantly, the DPBS solution can be used as a substitute in biomimetic solution for apatite coating at low processing temperatures for bioactive coating of the medical implant.
Nurul Hazwani Hanib, Fazlena Hamzah, Zarina Omar and Istikamah Subuki, 2019. Biomimetic Apatite Deposition in Modified Dulbecco’s Phosphate-Buffered Saline Solution on the Alkali-Heat Treated TI6AL4V. Journal of Engineering and Applied Sciences, 14: 3083-3093.