Authors : Aseel M. Aljeboree, Ayad F. Alkaim, Firas H. Abdulrazzak, Ahmed S. Abbas and Abbas Noor Alshirifi
Abstract: During the 1990’s, pharmaceutically active compounds such as lipid regulating drugs, analgesics, antibiotics, antiseptics, hormones and chemotherapy and beta-blocking heart drugs were detected in wastewaters, streams and ground-water resources across. A simple, sensitive and selective spectrophotometric methods have been developed for the quantitative estimation of some antibiotic drugs. The method involves the formation oxidative coupling of drug using 4-aminoantipyrine. The method (Oxidative coupling) is based on the condensation of aminoantipyrine with phenols in the presence of an alkaline oxidizing agent to yield coloured product the absorbance of which is monitored at wavelengths.
Aseel M. Aljeboree, Ayad F. Alkaim, Firas H. Abdulrazzak, Ahmed S. Abbas and Abbas Noor Alshirifi, 2019. Spectrophotometric Determination of Pharmaceutical by Oxidative Coupling of 4-Aminoantipyrine: A Short Review. Journal of Engineering and Applied Sciences, 14: 5561-5569.