Abstract: This study presents experimental investigation and numerical analysis of the flexure behavior of interior beam-column joints made from hybrid concrete (Normal Concrete (NC) and Steel Fiber Reinforced Concrete (SFRC)) or hybrid reinforcement (steel and CFRP bars internally or externally by NSM technique). Nine hybrid reinforced concrete beam-column joint specimens under effect of static or repeated loading with pre-axial compression load were studied and tested within three test groups. Several variables that effect on the behavior of beam-column connection region are investigated such as type of loading (static or repeated), type of hybridization (concrete hybridization or reinforcement hybridization), area of concrete hybridization and the joint enlargement technique. The results showed that using SFRC as replacement concrete at different areas of BCJ under static loading, improved the ultimate load capacity and first, cracking load about (7-13%) and (0-27%), respectively, compared with reference NC joint with increase in the ductility about (11-30%). As well as using the same technique under repeated loading condition showed increasing in ultimate load about (14.3%) with improvement a cumulative ductility about (13%) compared with the reference NC joint. The joint enlargement technique by using SFRC produced increasing of ultimate and first, cracking loads about (27%) and (67%), respectively. On the other hand using CFRP bars as (internal or external) hybridization system (50% of main reinforcement) under static loading caused increments of ultimate and first, cracking loads about (18, 5%) and (33, 67%), respectively, compared with the reference steel reinforced joint while the ductility ratio decreased about (7.4%) and increased about (14%), respectively. As well as the internal hybrid reinforcement system exhibited reduction in a cumulative ductility about (12.5%) under repeated loading. In the numerical analysis, non-linear three dimensional finite elements solution scheme utilizing ANSYS computer program (Version 14.5) was adopted. Comparison between the theoretical and experimental results exhibited reasonable agreement.