Abstract: This study shows an effective deformable complex 3D image reconstruction and image synthesis technique by consolidating needed high-level features from Convolutional Neural Network (CNN) system. By recognize inherent deep feature representations in image patches for morphological changes in medicinal imaging information discovery. Utilizing the ADNI and LONI imaging datasets, image reconstruction and synthesis performance was verified with two existing design. Various performance measurements, High Frequency Error Norm (HFEN), Mean Squared Error (MSE), peak Signal-to-Noise Ratio (PSNR), Structural Similarity Index (SSI) are utilized to inspect different dataset. A deformable image reconstruction and synthesis strategy that uses conventional features has low value of MSE and HFEN. Likewise, to reveal the adaptability of the proposed image reconstruction and synthesis system, synthesis and reconstruction experiments were directed on 7T cerebrum MR image. As presented in the paper outcomes, the proposed method can accomplish predominant performance compared with other cutting-edge techniques with either low or high-level features in terms of the synthesis and reconstruction rate. In all investigations, the outcome shows that the proposed image synthesis and reconstruction framework reliably exhibited progressively precise outcomes when contrasted with best in class. Hence, it can be used for possible precise image reconstruction and synthesis related applications.