Authors : Khatarina Meldawati Pasaribu, Saharman Gea, Syafruddin Ilyas and Tamrin Tamrin
Abstract: Bacterial Cellulose (BC) has the ability as tissue scaffolding, since, this material has excellence properties including high water holding capacity, high crystallinity as well as elasticity. This research focused on investigating the fabrication of bacterial cellulose-based compisites for skin tissue engineering. BC was produced via agitated culture medium while its adding with chitosan and collagen were obtained through ex-situ method which was done by immersing BC pellicles to chitosan or collagen solution for 24 h. Based on the Thermal Gravimetric Analysis (TGA), the scaffold material BC-Chitosan-Collagen gave a rising value of temperature which was 35.43°C for 1% mass loss, implying the improvement of thermal properties of materials. From Differential Thermal Analysis (DTGA), it is recorded that Tmax of BC-collagen is 330°C. Scanning Electron Microscope (SEM) shows that the presence of chitosan and collagen into BC fibers resulted in a well-interconnected network structure. These results imply that BC-based composites with collagen or chitosan can serve for skin tissue engineering.
Khatarina Meldawati Pasaribu, Saharman Gea, Syafruddin Ilyas and Tamrin Tamrin, 2020. Fabricated Bacterial Cellulose-Based Composites for Skin Tissue Engineering. Journal of Engineering and Applied Sciences, 15: 1640-1644.