Abstract: The study looked into the attitude of health workers in Calabar and their views on problems militating against health care services for the handicapped persons in Nigeria. All health workers in both public and private health establishment in Calabar were used as population of the study. Two hundred and sixty five health workers reacted to a 20 item validated questionnaire as subjects of the study. Simple descriptive statistical analysis such as ratio, percentage and tables were used to analyse the data collected from subjects of the study. The study revealed that health workers had negative attitude towards handicapped persons and that lack of funds and relevant health/medical equipment and facilities constituted problems in the health care services of the handicapped persons in Calabar, Nigeria Dearth of health and medical literature in the various health care establishments was also identified as a major problem. The Study recommended attitudinal change on the part of health workers and introduction of free medical services for the handicapped persons in Nigeria. A more positive approach by members of the public especially friends and relations to the health of handicapped persons was also recommended.