Abstract: The purpose of this study was to investigate the relationships of emotional intelligence and self-efficacy to work attitudes of secondary school teachers in southwestern Nigeria. The sample consists of 475 secondary school teachers (males = 230, females = 245) randomly selected from southwestern Nigeria. Measures of demographic data form, career commitment, organizational commitment, emotional intelligence, self-efficacy and work-family conflict were administered to the teachers. Data collected were analysed using hierarchical multiple regression analysis. Results of the study indicate that emotional intelligence and self-efficacy had significant relationships with work attitudes. However, age, sex and work experience had none. The implications of the findings for selection, training, counselling and retention of teachers were discussed. It was recommended that emotional intelligence and self-efficacy of the teachers should be enhanced to improve their work attitudes.