Abstract: A woman`s attitude towards breastfeeding and how she chooses to feed her baby are closely linked to the woman`s culture. In evaluating the cultural impact on breastfeeding, one can ask the woman about where she grew up and if her mother, aunts or friends have breastfed a baby and what support from family or friends they had. Although, it has been generally accepted that breastfeeding has valuable effects on nutritional, immunological and emotional aspects of infants� health. However, the tendency of some mothers toward bottle-feeding should not be denied, therefore we planned this study to find out how families cultural factors and specially previous feeding of mothers during their infancy can influence their adherence to breastfeeding of their infants. This is a cross-sectional and analytical study on 200 healthy infants at the age of 5 to 6 months who had come in Infants� Growth-Surveillance Clinic of Tabriz Children�s Hospital (affiliated to Tabriz University of Medical Sciences) during one year from March 2005 to March 2006. The eligible infants were consecutively enrolled and allocated in two groups upon their type of feeding: breastfed versus bottle-fed, every volunteer mother passed an interview with a trained medical staff that gathered and recorded the needed data by completing a questionnaire. Selection and allocation of participants was terminated for each group when it reached to a total number of 100 infants. Total 72% of mothers in breastfed group themselves had received breastfeeding during infancy, while only 41% of mothers in bottle-fed group had previous history of being breastfed. This difference is statistically significant: p = 0.0001, it shows a meaningful correlation between mothers` feeding during their infancy and their decision in choosing the feeding method of their own infants.The most important causative factors for beginning of bottle-feeding in this study was revealed to be lack of maternal motivation for breastfeeding (reported in 69% of mothers of bottle-fed infants) and also physicians` prescription of formula (in 22%). Breastfeeding rates can be increased by appropriate cultural background and skilled lactation support, worksite facilities for breastfeeding mothers, accommodation for human-milk feeding in child care settings and appropriate legislation.