Abstract: Globalization has brought about the interdependence of the economic systems of many nation, Nigeria inclusive. The collapse of the global financial markets resulting in decline in employment, soaring food prices among others has triggered similar problems in Nigeria. This study examined how the Global Financial Crisis (GFC) has affected the poverty level in Nigeria in view of the fact that economic factors are usually blamed for the trafficking in women and children. Secondary sources were used to generate data used to examine what implications the GFC portends for Nigeria in the area of human trafficking. The study revealed that GFC has heightened poverty in Nigeria. The implications of which are violation of the rights of children and further poverty as a result of reduced women’s contributions in the agricultural sector among others. It was recommended that poverty reduction measures should be emphasized and strengthened while also addressing the issue of infrastructural decay in order to arrest decline of small and medium enterprises.