Abstract: With the transition to a bachelor degree the training time reduced and the number of disciplines was not decreased, so the emphasis is on independent work of students to maintain the level of student preparation. The urgency of the problem stated in the study is conditioned by the fact that at the traditional form of independent student work organization in mathematics there are difficulties in the study of this discipline, the lack of study sources of information, etc. So, one needs to organize an independent work properly and efficiently through information technologies. The purpose of the study is to develop methods of using information technology in the organization of independent work of students. The leading method in the study of this problem is a design method aimed at the selection and structuring of electronic educational resource content on the subject “Mathematics” in Moodle environment. The developed electronic educational resource for the students of non-mathematical professions includes the following topics: the elements of linear algebra, analytic geometry, mathematical analysis and differential equations. The created electronic educational resource is aimed at the improvement of student knowledge on mathematics and promotes the development of self-employment among students. An experimental study was conducted in 2013-2014, on the basis of biological department at Elabuzhsky Institute of Kazan (Volga region) Federal University. The students of the following areas of training took part in this study: 06.03.01 Biology, “General Biology” profile and 44.03.05. Teacher education, “Biology and Chemistry” profile.