Research Journal of Biological Sciences

Year: 2012
Volume: 7
Issue: 1
Page No. 48 - 51

Biological Evaluation of Some Azole Derivatives in Cooling Fluids (Lubricant Oils)

Authors : Firas Abdullah Hassan and Khalid Waleed Younus

Abstract: In the present study, a series of five members heterocyclic where used as antimicrobial against the pseudomonas bacteria which have been found in the cooling fluids of industrial purposes. The results showed that the compounds 3 and 5 are relatively higher percentage in killing bacteria than other compounds used in this research indicating that from measuring pH, turbidity and culture media to inhibit the pseudomonas bacteria. After measuring the microorganisms growth of cooling fluids in 3 different periods (1 day, 1 and 2 weeks) by using pH and turbidity measurements enhanced with media culture method, the 2 weeks sample had been taken which showed highest growth of microorganisms meanwhile these azoles derivatives have been used as antimicrobial against the microorganisms which have been found in the cooling fluid of industrial purposes by measuring pH and turbidity enhanced with media culture the results showed that the compound 5 had the best biological activity then compounds 1 and 3 are relatively higher active in killing bacteria from the compounds 2 and 4. That azoles derivative is biologically active as antimicrobial agents in cooling fluids as derivatives of azoles have used as follows: [5- (2,4-dinitrobenzamide)-2-hydrazine]-thiadiazole, 2-mercapto-1, 3, 4-triazole-2, 4-dinitrobenzamide), Dithiophen oxadiazole, Thiophene/furan oxadiazole and Phenyl/pyridine oxadiazole.

How to cite this article:

Firas Abdullah Hassan and Khalid Waleed Younus, 2012. Biological Evaluation of Some Azole Derivatives in Cooling Fluids (Lubricant Oils). Research Journal of Biological Sciences, 7: 48-51.

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