Abstract: Advantages or disadvantages of calorie restriction as a factor for reducing Coronary Artery Disease (CAD) risk factors have been questioned. In the present study, researchers examined the effects of a short-term dietary calorie intake on laboratory parameters related to the risk factors for CAD, especially serum creatinine rise in patients with CAD. In a cross-sectional study, 444 consecutive patients with the diagnosis of CAD and candidate for coronary artery bypass surgery were participated in this study. Laboratory parameters as CAD risk factors were measured. Energy intake was estimated from the self recorded dietary intake records so that the energy content of the entire diet is computed as the sum of the energy available in each food item consumed. Linear regression analysis showed no significant relationships between dietary energy intake and laboratory parameters of fasting blood glucose, lipoprotein and lipid profiles, however in both obese and non-obese groups, there were adverse relationships between dietary energy intake and last serum creatinine. In mutivariate analysis, after adjusting for confounders, significant adverse relationship was found between dietary energy intake and serum creatinine concentration.
Majid Kolahdouzan, Mojgan Gharipour and Behnaz Nikkar Esfahani, 2013. Effect of Dietary Energy Intake on Risk Factors for Coronary Artery Disease with the Focused on Serum Creatinine Concentration. Research Journal of Biological Sciences, 8: 94-98.