Authors : K.O. Oyedeji and A.F. Bolarinwa
Abstract: The aim of this study was to investigate the effects of aqueous and methanolic extracts of Portulaca oleracea designated as AEPO and MEPO, respectively on estrous cycle and histopathology of the ovaries and uteri in female Albino rats. Treatments of rats for 21 days with 75 mg kg-1 BW AEPO produced no significant (p>0.05) change in the duration of all the phases of estrous cycle. Likewise, treatment of rats for 21 days with 75 mg kg-1 BW MEPO produced no significant (p>0.05) change in the duration of all the phases of estrous cycle. Treatment of rats for 25 days with 75 mg kg-1 BW AEPO and MEOP produced no significant (p>0.05) change in the ovarian and uterine weights of the treated rats relative to the control. Treatment of rats for 25 days with 75 mg kg-1 BW AEPO and MEPO induced no pathologic lesions or effects in both the ovaries and uteri of the treated rats. These findings indicate that AEPO and MEPO have no deleterious effects on the reproductive functions of female Albino rats.
K.O. Oyedeji and A.F. Bolarinwa, 2013. Evaluation of the Reproductive Functions of Portulaca Oleracea Extracts in Female Albino Rats. Research Journal of Pharmacology, 7: 1-6.