Abstract: This study discusses contemporary environmental health issues with the aid of empirical models for three residential zones in Akure, South west of Nigeria. The study begins with a general introduction to urban environment/health relationships. Thereafter, it goes on to discuss the attributes of the study area. For its methodology, the study made use of hierarchical sampling procedure to select household heads across residential districts of Akure town for a socio economic survey. The responses were collated while dummy variables germane to urban health relationships in the residential zones were fed into three models prescribed for the analysis. The models returned �robust goodness of fit values� of 0.844, 0.902 and 0.711, respectively. The implications of the performance of the variables were discussed. The study noted among other findings that wastewater management, age of buildings, domestic water supply, management of gaseous wastes in buildings and mode of feacal waste management are critical issues in the study area. Appropriate policy recommendations were proffered in the study.