Abstract: This study examined the potential role of big data in chemistry education research. Big data refer to data sets that are too large or complex for traditional data processing application software to adequately deal with. With large amounts of information streaming in from countless sources, chemistry education researchers are faced with finding new and innovative ways to manage big data. Chemistry education researchers armed with data-driven insight can make a significant impact on school systems, students and curriculums. By analyzing big data, they can identify at-risk students, make sure students are making adequate progress and can implement a better system for evaluation and support of chemistry teachers and school administrators. With big data, chemistry education researchers and educators can identify root causes of chemistry student’s failures issues and defects in near-real time and detecting fraudulent behaviour among chemistry students among others.